A team of researchers from the University of McMaster, in Canada, identified a partial and they described as “Signatures of the candidate” To become a new category of Antibiotics: This is it Larosidin. According to researchers, this molecule attacks bacteria in a different way from other antibiotics, which can be used “to challenge some of the drug bacteria.” Scientists explained the results of their research in an article conducted by the scientific journal Nature, in which other research groups from various countries participated.
This discovery responds to the decisive need for new antimicrobial drugs, because bacteria and other microorganisms develop new ways to resist existing drugs. This resistance, as a statement from McMaster University explained, One of the main threats of public health On this planet, according to the World Health Organization.
“Our old drugs are less effective and less effective as bacteria become more resistant to them,” says Jerry Wright, who brought out the team. It confirms that about 4.5 million people die every year due to antibiotic -resistant infections and the situation does not get worse. Wright and his team discovered that The new molecule “is very promising” As the first drug idea because it attacks bacteria in a different way from other antibiotics.
Scientists are optimistic about the characteristics of their resistance
Larrisidine is produced by a type of bacteria called Paenibacillus, which the researchers obtained The soil sample A group in the backyard of Hamilton (the city where the university is located). This joins the mechanism of protein synthesis of bacteria in a completely new way, which prevents its ability to grow and survive. “This is a new molecule with a new way of working,” Wright summarizes.
The researchers noticed how the soil sample bacteria slept for a year in the laboratory, until they noticed that one of these bacteria (Paenibacillus), produced, A very active new material against other bacteriaIncluding those that are usually resistant to antibiotics.
Scientists are optimistic, given the properties of Larrisidine that meet many requirements: It is not toxic to human cellsIt is not vulnerable to the current mechanisms to resist antibiotics and works well in the animal infection model.
