The first is born in the fertilized laboratory through a robot led by artificial intelligence
One of the main developments of reproductive sciences was an evolution In fertilization in the laboratory (IVF). Now, one of the most important developments, artificial intelligence (Amnesty International), joined for the first time, A child was born in the laboratory Thanks for an artificial intelligence process.
IVF method is sperm injection inside (ICSI), where a single sperm is injected into ripe eggs into a laboratory plate. This process has been developed in the 1990s and is now widely used in male infertility cases, as it means that sperm should not be swimming to reach the egg. Then the resulting embryos are inserted into the uterus.
Another way to fertilize eggs is to mix them with sperm on a laboratory dish. This method requires Less medical intervention, but it is less accurate, So it is generally less successful. But the ICS (individually sperm injection into eggs) can also be a victim of human errors.
ICSI procedures are performed manually by trained embryologists using accurate financing systems. It requires a high level of accuracy and studies that showed that the performance of embryos that ICSI can vary greatly between individuals.
Jack CohenThe perceived life sciences, a biotechnology company in New York City, explains to New world: “Sometimes they get tired and distracted, like anyone else in most professions, so errors that can reduce fertilization and births.”
To address this problem, Dr. Cohen and his colleagues have developed a machine You can take the 23 main steps Necessary for standard ICSI.
The device can be operated independently by artificial intelligence (AI) or pressing a button. One step means that the device uses AI model Select the most healthy sperm To enrich, according to your appearance.
After that, it makes the device easier Sperm When their laser tails are beaten and fixed, before they are injected into the eggs that were already collected.
“With artificial intelligence, The system is independently chosen sperm It is accurately gathered by an average section with a ready -made laser, and the implementation of this rapid and accurate process is accurately exceeding human capabilities. “
It is used for Put the sperm on the injection pipette And put it in the egg. This ICSI system is the only output to automate each subtle financing procedures, with additional management steps and selection of sperm made by.
Cohen says ICSI’s automation “is a transformative solution promising to improve accuracy, improve efficiency and ensure consistent results.” Reducing the burden of human operators And ensuring a decrease in contrast in procedures.
The automatic process can also Improving egg survival It improves injection time, adds Cohen.
This was the process
To test their project, the researchers recruited a 40 -year -old woman derived for treatment with donor eggs at IVFR in Guadalakara, MexicoAfter a failed attempt previously.
Women have had difficulty producing eggs, so one of the donors was used, because the sperm of her partner was unable to swim properly. They were enriched Five eggs with ICSI automatic And three controls, as they were injected from sperm with a standard ICSI guide.
The automated system has been installed in the clinic, but scientists manage the device remotely, From the Guadalajara and New York clinic, Issuing orders through a digital interface to perform each of the 23 minute financing steps for each egg.
In general, the entire procedure continued 9 minutes and 56 seconds Through the egg, a little more routine ICSI due to its experimental nature. But Professor Mendesapal Ruiz says, “We hope he will significantly reduce the time of the procedure.”
Four of the five eggs injected into the automated system reached a natural fertilization and all three in the manual control group. team The fetus was entered It was produced through the womb of the woman, but it did not develop. However, the second led to the child’s healthy birth.
