New biological tools make revolutionary changes in the fight against brain diseases
These tools allow the correction of genetic defects in specific cells without affecting the surrounding cells, opening new opportunities for accurate neurology treatments.
The mouse is one of the new genetic tools developed on the Alen Institute of different cell population in the brain.
Instituto Allen
A set of new biological tools has been developed to deal with brain disease and open doors for genetic treatments directed.
These ferremens have called Potential Vectors, Aden-All-(or AAV) virus, performed in A A series of eight studies published in Cell MagazineResearchers of 29 universities and institutions led by the United States’s Allen Institute participated.
The ability of these new tools allows genetic defects to be corrected in specific cells that contribute to the disease without affecting the surrounding cells or adding unwanted side effects.Said the Institute.
New tools have revealed themselves “The most effective in detecting specific brain cells and allowed scientists to edit cell activities and animal behavior” According to the same source.
The harmless virus
AAV potential vectors have harmless ade-connecting virus, which works A shot that can be transported specifically inside the cell.
There is also the DNA section that serves as a “activation switch” to identify or induce a change in cell function.
Diseases are often caused by failures in specific types of cells and not across the organism, so Epilepsy is a disease of specific nervous system neurons.
Taking the right cells, “the right and proper time, the future of the perfect brain medicine” and these tools bring us to this future, while at the same time expands what is known about cells and brain circuits, “said Brain Director John Ngai.
Researchers have performed the benefits of cell selection in the recent innovation related to Dravet Syndrome.
In addition, in a study, they were able to detect and identify the rare cell that controls sleep, open the doors for new treatments for sleep interruptions.
Genetic tools are also designed for a variety of brain cells, including cortex, striamum and brain areas of the spinal cord.
